Benzocaine-Adultered Street Cocaine in Association with Methemoglobinemia

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Benzocaine-adultered street cocaine in association with methemoglobinemia.

A 27-year-old man with a history of cocaine abuse ingested a large quantity of street cocaine in an apparent suicide attempt. Shortly thereafter, he developed tonic-clonic seizures and became cyanotic. An arterial blood gas sample, collected in the emergency department, appeared chocolate-brown and showed pO2 279 mmHg, pCO2 53 mmHg, and pH 7.15. Hemoglobin spectral analysis revealed significant...

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Benzocaine-induced methemoglobinemia.

A case is reported in which a patient developed methemoglobinemia-induced cyanosis while under general anesthesia during surgery for multiple fascial space infections. The cause of methemoglobinemia was 20% benzocaine spray used for local anesthesia before intubation. Acutely developing methemoglobinemia is infrequently encountered in clinical practice. When confronted with cyanosis in the abse...

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Benzocaine-Induced Methemoglobinemia: A Case Report.

Topical anesthetics, such as benzocaine, have been reported to cause methemoglobinemia, in which hemoglobin is unable to release oxygen effectively to body tissues. The pathophysiology, symptoms, and treatment of a 46-year-old patient are examined.

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Acute Methemoglobinemia Secondary to Topical Benzocaine Spray

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Benzocaine-induced methemoglobinemia during transesophageal echocardiography.

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1992

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/38.4.596